Boostrix Polio should not be administered to subjects with known hypersensitivity to any component of the vaccine (see Description) or to subjects having shown signs of hypersensitivity after previous administration of diphtheria, tetanus, pertussis or poliomyelitis vaccines.
Boostrix Polio is contraindicated if the subject has experienced an encephalopathy of unknown aetiology, occurring within 7 days following previous vaccination with pertussis-containing vaccine. In these circumstances, pertussis vaccination should be discontinued and the vaccination course should be continued with diphtheria, tetanus and poliomyelitis vaccines.
Boostrix Polio should not be administered to subjects who have experienced neurological complications following an earlier immunization against diphtheria and/or tetanus (for convulsions or hypotonic-hyporesponsive episodes, see Precautions).